Massif-1 at MASSIF-1 and fragment-based drug design
نویسندگان
چکیده
منابع مشابه
1 Introduction to Fragment - based Drug Discovery
Fragment screening is the process of identifying relatively simple, often weakly potent, bioactivemolecules. It is gainingwide acceptance as a successful hit-finding technique both in its own right and as a method of finding hit molecules when traditional high-throughput screening (HTS) methods fail. Fragment hits are typically highly ‘ligand efficient’, i.e. possess a high binding affinity per...
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ژورنال
عنوان ژورنال: Acta Crystallographica
سال: 2022
ISSN: ['2053-2733']
DOI: https://doi.org/10.1107/s2053273322097923